产品货号：
Z29739
中文名称：
uPAR/PLAUR抗体
英文名称：
Anti-uPAR/PLAUR Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-uPAR/PLAUR Antibody |
| 指标别名 | CD87;MO3;PLAUR;U PAR;UPAR;URKR |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | PLAUR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human uPA Receptor(293-304aa CNHPDLDVQYRS). |
| 实际分子量 | 37～65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR,UROKINASE-TYPE),also known as UPAR or CD87,is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol(GPI) anchor.PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family.PLAUR is originally identified as a saturable binding site for urokinase on the cell surface.And the gene plays an important role in many normal as well as pathologic processes.The PLAUR gene is localized to 19q13.31.PLAUR is a part of the plasminogen activation system,which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing.PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane.Thus it seems to be an important player in the regulation of this process.In human coronary artery vascular smooth muscle cells,UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase. |
| Uniprot ID | Q03405 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | plasminogen activator,urokinase receptor |
| 蛋白名全称 | Urokinase plasminogen activator surface receptor(U-PAR/uPAR) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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